USB and Bluetooth Device Problems and Mouse Click Failures on a Custom PC: How to Identify and Solve Them


What could be causing my USB and Bluetooth peripherals to randomly disconnect and my mouse clicks to fail, and how can I fix it?

I have a custom-built PC with the following specifications:

  • CPU: AMD Ryzen 5 5600G – Ryzen 5 5000 G-Series Cezanne (Zen 3) 6-Core 3.9 GHz Socket AM4 65W AMD Radeon Graphics Desktop Processor – 100-100000252BOX
  • CPU Cooler: CORSAIR iCUE H150i ELITE CAPELLIX Liquid CPU Cooler LGA 1700 Compatible – White
  • Case: CORSAIR iCUE 5000X RGB Tempered Glass Mid-Tower ATX PC Smart Case, White, CC-9011213-WW
  • Power Supply: CORSAIR CX-F RGB Series CX550F RGB White 550W 80 PLUS Bronze Fully Modular ATX Power Supply, CP-9020225-NA
  • RAM: CORSAIR Vengeance RGB Pro SL 16GB (2 x 8GB) 288-Pin PC RAM DDR4 3600 (PC4 28800) Desktop Memory Model CMH16GX4M2D3600C18W
  • Graphics Card: GIGABYTE AORUS GeForce RTX 3060 ELITE 12G Graphics Card, 3 x WINDFORCE Fans, 12GB 192-bit GDDR6, GV-N3060AORUS E-12GD Video Card
  • Motherboard: ASRock B550M PRO4 AM4 AMD B550 SATA 6Gb/s Micro ATX AMD Motherboard
  • Hard Drive: Seagate BarraCuda ST2000DM008 2TB 7200 RPM 256MB Cache SATA 6.0Gb/s 3.5″ Hard Drive Bare Drive
  • SSD: SAMSUNG 970 EVO PLUS M.2 2280 1TB PCIe Gen 3.0 x4, NVMe 1.3 V-NAND Internal Solid State Drive (SSD) MZ-V7S1T0B/AM
  • Operating System: Microsoft Windows 10 Home, 64-bit, DVD – OEM
  • The problems I am experiencing are:

  • Random peripheral disconnects during high-resource applications (e.g., gaming) and occasionally during web browsing.
  • Random Bluetooth device disconnects, sometimes leading to the disappearance of Bluetooth adapter from the device manager, affecting Bluetooth functionality all together.
  • System occasionally stops recognizing mouse clicks across all active windows except the window I was working in when the problem occurs (usually a game), requiring CTRL-ALT-DEL to regain control temporarily. Occurrence of issues just moments after booting up, with the system becoming unresponsive every 30 seconds. While working in the one window is possible, the taskbar, start menu, and all other windows remain unresponsive to mouse clicks.
  • Random tabbing out of games.
  • Random key presses occurring without input.
  • Random, brief disconnects and reconnects of peripherals (mouse, keyboard, headset). This is especially annoying as when this happens my microphone is no longer recognized and a revoke of access and giving it back is required for me to able to speak until it disconnects again.
  • I have tried the following solutions, but none of them worked:

  • Contacting Microsoft customer support and troubleshooting to level 3 support.
  • Doing a fresh install of windows to my system.
  • Installing drivers for the Bluetooth adapter, graphics drivers, updated BIOS, installed chipset drivers, removed faulty devices in device manager, and unplugged everything and restarted and then plugged peripherals back in.
  • Performing a factory reset, adjusting battery-saving settings to allow USB ports to maintain power, and clearing static electricity.
  • I have noticed that when this happens there is a short spike in CPU use to 100% so I believe this is the cause, but I am unsure. Another thought is that apart from the dedicated GPU there is an integrated graphics in the CPU and since this problem usually occurs when starting a game and then randomly while playing I was speculating a problem with having two graphics processors, but again I am unsure.

    I have found some forums that describe similar issues to what I am experiencing:

  • [After a while mouse click fails and only ctrl alt del brings back the functionality](
  • [Mouse click fails and only ctrl alt del brings back the functionality](
  • I

would appreciate any expert advice on how to resolve this issue. Thank you.


If you are experiencing random disconnects and reconnects of your USB and Bluetooth devices, as well as mouse click failures, you are not alone. Many users have reported similar issues on various forums and websites, and there are several possible causes and solutions for this problem.

Possible causes

Some of the possible causes for your USB and Bluetooth peripheral disconnects and mouse click failures are:

  • Faulty or incompatible drivers: Drivers are software components that enable your operating system to communicate with your hardware devices. If your drivers are outdated, corrupted, or incompatible with your system, they may cause conflicts, errors, or malfunctions with your USB and Bluetooth devices and your mouse.
  • Power management issues: Your operating system may have power management settings that control the power supply to your USB and Bluetooth devices. If these settings are too aggressive, they may cause your devices to go into power-saving mode or turn off completely, resulting in disconnects and reconnects. Additionally, your power supply unit may not be able to provide enough power to all your devices, especially if you have a high-end graphics card or multiple peripherals connected.
  • Interference or signal issues: Your Bluetooth devices rely on wireless signals to communicate with your system. If there are other devices or sources of interference in your vicinity, such as Wi-Fi routers, microwaves, cordless phones, or other Bluetooth devices, they may interfere with your Bluetooth signal and cause disconnects or poor performance. Similarly, your USB devices may have loose or damaged cables or ports that affect their connection quality.
  • Hardware defects or incompatibilities: Your USB and Bluetooth devices, your mouse, or your system components may have hardware defects or incompatibilities that cause them to malfunction or fail. For example, your USB or Bluetooth adapter may be faulty or incompatible with your motherboard, your mouse may have a broken sensor or button, or your CPU may have overheating or performance issues.
  • Possible solutions

    Some of the possible solutions for your USB and Bluetooth peripheral disconnects and mouse click failures are:

  • Update or reinstall your drivers: You can try to update or reinstall your drivers for your USB and Bluetooth devices, your mouse, and your system components. You can use the device manager, the manufacturer’s website, or a third-party tool to find and install the latest and compatible drivers for your devices. You can also uninstall and delete any drivers that are not in use or that may cause conflicts with your devices.
  • Adjust your power management settings: You can try to adjust your power management settings to prevent your USB and Bluetooth devices from going into power-saving mode or turning off. You can do this by going to the control panel, the device manager, or the power options, and changing the settings for your USB and Bluetooth devices, such as disabling the option to allow the computer to turn off this device to save power, or increasing the USB selective suspend setting. You can also check your power supply unit and make sure it can provide enough power to all your devices, or replace it with a more powerful one if needed.
  • Reduce interference or improve signal quality: You can try to reduce interference or improve signal quality for your Bluetooth devices by moving them closer to your system, changing their frequency or channel, or removing any sources of interference in your vicinity. You can also check your USB devices and make sure they have secure and undamaged cables and ports, or replace them if needed.
  • Check your hardware for defects or incompatibilities: You can try to check your hardware for defects or incompatibilities by running diagnostics, testing them on another system, or contacting the manufacturer or a professional for assistance. You can also try to replace any faulty or incompatible hardware with new or compatible ones, or upgrade your system components if they are outdated or underperforming.
  • Conclusion


conclusion, your USB and Bluetooth peripheral disconnects and mouse click failures may be caused by various factors, such as faulty or incompatible drivers, power management issues, interference or signal issues, or hardware defects or incompatibilities. You can try to solve this problem by updating or reinstalling your drivers, adjusting your power management settings, reducing interference or improving signal quality, or checking your hardware for defects or incompatibilities. Hopefully, one of these solutions will work for you and restore your device functionality and performance.

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